2020-10-19

1: Yang CY, Liu Y, Lu Z, Ren R, Gong H. Effects of Y27632 on aqueous humor outflow facility with changes in hydrodynamic pattern and morphology in human eyes. Invest Ophthalmol Vis Sci. 2013 Aug 28;54(8):5859-70. doi: 10.1167/iovs.12-10930. PubMed PMID: 23920374; PubMed Central PMCID: PMC3757907.

2: Gandham VD, Maddala RL, Rao V, Jin JY, Epstein DL, Hall RP, Zhang JY. Effects of Y27632 on keratinocyte procurement and wound healing. Clin Exp Dermatol. 2013 Oct;38(7):782-6. doi: 10.1111/ced.12067. Epub 2013 May 16. PubMed PMID: 23675999; PubMed Central PMCID: PMC3748215.

3: Yu Z, Liu M, Fu P, Xie M, Wang W, Luo X. ROCK inhibition with Y27632 promotes the proliferation and cell cycle progression of cultured astrocyte from spinal cord. Neurochem Int. 2012 Dec;61(7):1114-20. doi: 10.1016/j.neuint.2012.08.003. Epub 2012 Aug 19. PubMed PMID: 22929997.

4: Huang HP, Wang CJ, Tsai JP, Wu SW, Hung TW, Lian JD, Chang HR. Y27632 attenuates the aristolochic acid-promoted invasion and migration of human urothelial cancer TSGH cells in vitro and inhibits the growth of xenografts in vivo. Nephrol Dial Transplant. 2012 Feb;27(2):565-75. doi: 10.1093/ndt/gfr366. Epub 2011 Jul 28. PubMed PMID: 21799205.

5: Lu Z, Zhang Y, Freddo TF, Gong H. Similar hydrodynamic and morphological changes in the aqueous humor outflow pathway after washout and Y27632 treatment in monkey eyes. Exp Eye Res. 2011 Oct;93(4):397-404. doi: 10.1016/j.exer.2011.05.012. Epub 2011 Jun 6. PubMed PMID: 21669200; PubMed Central PMCID: PMC3197945.

6: van Beuge MM, Prakash J, Lacombe M, Post E, Reker-Smit C, Beljaars L, Poelstra K. Increased liver uptake and reduced hepatic stellate cell activation with a cell-specific conjugate of the Rho-kinase inhibitor Y27632. Pharm Res. 2011 Aug;28(8):2045-54. doi: 10.1007/s11095-011-0430-9. Epub 2011 Mar 26. PubMed PMID: 21442374; PubMed Central PMCID: PMC3130909.

7: Balestrieri ML, Giovane A, Milone L, Felice F, Fiorito C, Crudele V, Esposito A, Rossiello R, Minucci PB, Farzati B, Servillo L, Napoli C. Modification of the detrimental effect of TNF-α on human endothelial progenitor cells by fasudil and Y27632. J Biochem Mol Toxicol. 2010 Nov-Dec;24(6):351-60. doi: 10.1002/jbt.20345. PubMed PMID: 20665603.

8: Sivasubramaniyan K, Pal R, Totey S, Bhat VS, Totey S. Rho kinase inhibitor y27632 alters the balance between pluripotency and early differentiation events in human embryonic stem cells. Curr Stem Cell Res Ther. 2010 Mar;5(1):2-12. PubMed PMID: 19951253.

9: Hampson L, He XT, Oliver AW, Hadfield JA, Kemp T, Butler J, McGown A, Kitchener HC, Hampson IN. Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 colonies. Br J Cancer. 2009 Sep 1;101(5):829-39. doi: 10.1038/sj.bjc.6605208. PubMed PMID: 19707205; PubMed Central PMCID: PMC2736836.

10: Freitas MR, Eto M, Kirkbride JA, Schott C, Sassard J, Stoclet JC. Y27632, a Rho-activated kinase inhibitor, normalizes dysregulation in alpha1-adrenergic receptor-induced contraction of Lyon hypertensive rat artery smooth muscle. Fundam Clin Pharmacol. 2009 Apr;23(2):169-78. doi: 10.1111/j.1472-8206.2008.00658.x. Epub 2009 Mar 9. PubMed PMID: 19298234; PubMed