中文名称: | Trametinib | ||||
---|---|---|---|---|---|
英文名称: | Trametinib | ||||
别名: | 曲美替尼 GSK1120212; | ||||
CAS No: | 871700-17-3 | 分子式: | C26H23FIn5O4 | 分子量: | 615.39 |
CAS No: | 871700-17-3 | ||||
分子式: | C26H23FIn5O4 | ||||
分子量: | 615.39 |
一种口服有效的MEK抑制剂。
Trametinib is a n orally bioavailable inhibitor of mitogen-activated protein kinase kinase (MEK MAPK/ERK kinase) with potential antineoplastic activity. Trametinib specifically binds to and inhibits MEK 1 and 2, resulting in an inhibition of growth factor-mediated cell signaling and cellular proliferation in various cancers. MEK 1 and 2, dual specificity threonine/tyrosine kinases often upregulated in various cancer cell types, play a key role in the activation of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )