中文名称: | Sertraline hydrochloride | ||||
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英文名称: | Sertraline hydrochloride | ||||
别名: | (1S,4S)-4-(3,4-二氯苯基)-N-甲基-1,2,3,4-四氢萘-1-胺盐酸盐;盐酸舍曲林 (1S,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride | ||||
CAS No: | 79559-97-0 | 分子式: | C17H17NCl2.HCl | 分子量: | 342.69 |
CAS No: | 79559-97-0 | ||||
分子式: | C17H17NCl2.HCl | ||||
分子量: | 342.69 |
包装规格:
1g 5g 25g 100g in glass bottle
溶解性:
溶于DMSO(50mg/mL超声)
产品描述:
一种选择性 5- 羟色胺再吸收抑制剂 (SSRI) 类的抗抑郁剂。Sertraline hydrochloride 用于研究多种疾病,例如重度抑郁症和强迫症。
Sertraline, also known as , is a selective serotonin uptake inhibitor that is used in the treatment of depression. Sertraline is primarily a serotonin reuptake inhibitor (SRI) with a binding affinity towards the serotonin transporter of Ki=2.8 nM or in that range. Sertraline is also a dopamine reuptake inhibitor, (<50 nmol/L). However, this is not considered a tight binding, and this action is only 10% of its potency as a monoamine reuptake inhibitor. It is a σ1 receptor agonist with 5% of its SRI potency, and an α1-adrenoreceptor antagonist with 1–10% of its SRI potency.
Sertraline, also known as , is a selective serotonin uptake inhibitor that is used in the treatment of depression. Sertraline is primarily a serotonin reuptake inhibitor (SRI) with a binding affinity towards the serotonin transporter of Ki=2.8 nM or in that range. Sertraline is also a dopamine reuptake inhibitor, (<50 nmol/L). However, this is not considered a tight binding, and this action is only 10% of its potency as a monoamine reuptake inhibitor. It is a σ1 receptor agonist with 5% of its SRI potency, and an α1-adrenoreceptor antagonist with 1–10% of its SRI potency.
保存条件:
-20℃ 充氮保存
UN码:
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危害声明:
安全说明:
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摩尔浓度计算公式
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稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )