中文名称: | SKLB610 | ||||
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英文名称: | SKLB610 | ||||
别名: | SKLB610 N-methyl-4-(4-(3-(trifluoromethyl)benzamido)phenoxy)picolinamide | ||||
CAS No: | 1125780-41-7 | 分子式: | C21H16F3N3O3 | 分子量: | 415.36 |
CAS No: | 1125780-41-7 | ||||
分子式: | C21H16F3N3O3 | ||||
分子量: | 415.36 |
一种VEGFR抑制剂,能有效抑制人肿瘤血管生成。
SKLB610 is a VEGFR inhibitor that potently suppresses human tumor angiogenesis. SKLB610 inhibited angiogenesis-related tyrosine kinase VEGFR2, fibroblast growth factor receptor 2 (FGFR2) and platelet-derived growth factor receptor (PDGFR) at rate of 97%, 65% and 55%, respectively, at concentration of 10μM in biochemical kinase assays. SKLB610 exhibited its antitumor activity as a multi-targeted inhibitor with more potent inhibition of VEGFR2 activity. Its potential to be a candidate of anticancer agent is worth being further investigated.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )