中文名称: | Ravoxertinib | ||||
---|---|---|---|---|---|
英文名称: | Ravoxertinib | ||||
别名: | Ravoxertinib GDC-099 | ||||
CAS No: | 1453848-26-4 | 分子式: | C21H18ClFN6O2 | 分子量: | 440.86 |
CAS No: | 1453848-26-4 | ||||
分子式: | C21H18ClFN6O2 | ||||
分子量: | 440.86 |
一种口服活性的ERK激酶抑制剂.
Ravoxertinib also known as GDC-0994, GDC994 and RG7842, is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, GDC-0996 inhibits both ERK phosphorylation and activation of ERK-mediated signal transduction pathways. This prevents ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )