中文名称: | 哌马色林 | ||||
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英文名称: | Pimavanserin | ||||
别名: | 哌马色林 ACP103 N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamide | ||||
CAS No: | 706779-91-1 | 分子式: | C25H34FN3O2 | 分子量: | 427.56 |
CAS No: | 706779-91-1 | ||||
分子式: | C25H34FN3O2 | ||||
分子量: | 427.56 |
一种选择性的5-HT2A受体反向激动剂,pIC50和pKd分别为8.73 and 9.3。
Pimavanserin is an inverse agonist on the serotonin receptor subtype 5-HT2A, with 40x selectivity over 5-HT2C, and no significant affinity or activity at 5-HT2B or dopamine receptors. Pimavanserin is a novel drug candidate for Parkinson's psychosis.Parkinson's disease psychosis (PDP) is a condition that may develop in up to 60 % of Parkinson's patients, and is a major reason for nursing home placement for those affected.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )