奥美拉唑钠 - CAS:95510-70-6 - CAS号查询_生物试剂_化学试剂_分析试剂

中文名称:	奥美拉唑钠促销
英文名称:	Omeprazole Sodium
别名:	奥美拉唑钠 Omeprazole Sodium
CAS No:	95510-70-6	分子式:	C₁₇H₁₉N₃NaO₃S	分子量:	367.4
CAS No:	95510-70-6
分子式:	C₁₇H₁₉N₃NaO₃S
分子量:	367.4

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O10163 奥美拉唑钠 ≥98% (psaitong)

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包装规格：

5g 25g 100g in poly bottle

产品描述：

基本信息

产品编号：	O10163
产品名称：	Omeprazole Sodium
CAS:	95510-70-6	储存条件	粉末	2-8℃	四年

分子式：	C17H19N3NaO3S		溶于液体	-80℃	6个月
分子量：	367.40			-20℃	1个月
化学名：	1H-Benzimidazole,6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-,sodium salt(1:1)
Solubility (25°C)：
体外:	DMSO	73mg/mL (198.69mM)
	Ethanol	73mg/mL (198.69mM)
	Water	73mg/mL (198.69mM)
体内(现配现用):
＜1mg/ml表示微溶或不溶。
普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

制备储备液

浓度溶液体积质量	1mg	5mg	10mg
1mM	2.7218mL	13.6091mL	27.2183mL
5mM	0.5444mL	2.7218mL	5.4437mL
10mM	0.2722mL	1.3609mL	2.7218mL

生物活性

产品描述

一种质子泵(proton pump)抑制剂。

靶点

Proton Pump

Autophagy

Bacterial

Phospholipase

体外研究

Omeprazole (H 16868) is a proton pump inhibitor used in the treatment of dyspepsia,peptic ulcer disease,gastroesophageal reflux disease,laryngopharyngeal reflux,and Zollinger-Ellison syndrome.Omeprazole (H 16868) virtually eliminated intragastric acidity in all patients:the median 24 hour intragastric pH rose from 1.4 to 5.3 and the mean hourly hydrogen ion activity fell from 38.50 to 1.95 mmol(mEq)/1 (p less than 0.001).This inhibition of 24 hour intragastric acidity is more profound than that previously reported with either cimetidine 1g daily or ranitidine 300mg daily.The pharmacokinetics of omeprazole were studied in a group of healthy male subjects after single and repeated oral doses of 30 and 60mg.Absorption of Omeprazole (H 16868) from its enteric-coated formulation was unpredictable.There was a highly significant increase in the area under the plasma concentration time curve (AUC) after repeated dosing.Omeprazole (H 16868) increases its own relative availability following repeated dosing.This may be due to inhibition of gastric acid secretion by omeprazole which is an acid-labile compound.Omeprazole sodium is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).

保存条件：

2-8℃

UN码：

HazardClass：

危害声明：

安全说明：

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