中文名称: | L-689502 | ||||
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英文名称: | L-689502 | ||||
别名: | L-689502 Tert-butyl N-[(2S,3S,5R)-3-hydroxy-6-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-[[4-(2-morpholin-4-ylethoxy)phenyl]methyl]-6-oxo-1-phenylhexan-2-yl]carbamate | ||||
CAS No: | 138483-63-3 | 分子式: | C39H51N3O7 | 分子量: | 673.84 |
CAS No: | 138483-63-3 | ||||
分子式: | C39H51N3O7 | ||||
分子量: | 673.84 |
基本信息
产品编号:L10558 |
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产品名称:L-689502 |
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CAS: |
138483-63-3 |
储存条件 |
粉末 |
-20℃ |
四年 |
分子式: |
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分子量 |
673.84 |
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化学名: |
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Solubility (25°C) |
体外 |
DMSO |
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Ethanol |
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Water |
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体内 |
现配现用 |
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<1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
生物活性
产品描述 |
一个有效的 HIV-1 蛋白酶 (HIV-l protease) 抑制剂。 |
靶点/IC50 |
HIV-l protease IC50: 1nM |
体外研究 |
Both L694746 and L-689502 inhibit HIV-l ptotease activity in a concentration-dependent manner. Pepstatin is much less potent than either compound exhibiting an IC50 of 2μM. L694746 is as potent as L-689502 in inhibiting the HIV-l protease despite being structurally different from L-689502. |
推荐实验方法(仅供参考)
细胞实验: |
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Cell Assay |
G689502 (3.3 pmoles in 1mL of 100% DMSO) is added to cultures that have been growing for 48 hr. The final substrate and DMSO concentrations during the fermentation period are 65 pM and 2%, respectively. The fermentations containing L689502 are carried out for an additional 72-96 hr prior to be harvested.The whole broth is sequenthdly extracted with methanol (0.5 vol) and acetone (0.5 vol). The supematant containing the derivatives of L-689502 is separated from the mycelia by filtration. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )