洛草氨酸 - CAS:53882-12-5 - CAS号查询_生物试剂_化学试剂_分析试剂

安全技术说明书(PDF) MSDS(PDF) 点击下载产品说明书(PDF)

L10456 洛草氨酸 ≥98% (psaitong)

相关产品

包装规格：

100mg in glass bottle

溶解性：

溶于DMSO（50mg/mL 超声）

产品描述：

基本信息

产品编号：	L10456
产品名称：	Lodoxamide
CAS:	53882-12-5	储存条件	粉末	-20℃	四年

分子式：	C11H6ClN3O6		溶于液体	-80℃	6个月
分子量：	311.63			-20℃	1个月
化学名：	2,2'-((2-Chloro-5-cyano-1,3-phenylene)bis(azanediyl))bis(2-oxoacetic acid)
Solubility (25°C)：
体外:	DMSO
	Ethanol
	Water
体内(现配现用):
＜1mg/ml表示微溶或不溶。
普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

制备储备液

生物活性

产品描述	作为肥大细胞稳定剂的抗过敏化合物,用于研究哮喘和过敏性结膜炎。
靶点	Histamine Receptor
体外研究	Lodoxamide inhibits compound 48/80-induced histamine release and ionophore-induced 45Ca influx with associated histamine release in purified rat peritoneal mast cells.The chemotactic response of eosinophils to fMLP as well as to IL-5 is significant and dose-dependent inhibited by Lodoxamide.Lodoxamide is also able to strongly inhibit the release of eosinophil peroxidase after IgA-dependent activation and,to a lesser extent,the release of eosinophil cationic protein and eosinophil-derived neurotoxin.
体内研究	Lodoxamide has been demonstrated to have cromolyn-like activity when studied in the rat peritoneal mast cell assay (PCA) model3 and in Ascaris antigen-sensitized rhesus monkeys.When given intravenously,orally,or intrabronchially by aerosol,lodoxamide significantly inhibits the increased respiratory frequency and decreased tidal volume induced by antigen challenge in Ascaris-sensitized.anesthetized rhesus monkeys.Addition of lodoxamide tromethamine to Euro-Collins or University of Wisconsin solution results in a marked decrease in lung reperfusion injury as demonstrated by increased oxygenation,decreased microvascular permeability,and increased compliance.Patients treated with lodoxamide tromethamine demonstrate an improvement in daytime breathing difficulty,cough,sputum production,and sleep.

保存条件：

-20℃

UN码：

HazardClass：

危害声明：

安全说明：

搜索质检报告(COA)

参考文献 & 客户发表文献

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入输出 )