| 中文名称: | Litronesib | ||||
|---|---|---|---|---|---|
| 英文名称: | Litronesib | ||||
| 别名: | (-)-N-[4-(2,2-二甲基丙酰基)-5-[[2-(乙基氨基)乙磺酰胺]甲基]-5-苯基-4,5-二氢-1,3,4-噻二唑-2-基]-2,2-二甲基丙酰胺;(-)-N-[4-(2,2-二甲基丙酰基)-5-[[2-(乙基氨基)乙烷磺酰胺]甲基]-5-苯基-4,5-二氢-1,3,4-噻二唑-2-基]-2,2-二甲基丙酰胺 LY2523355 | ||||
| CAS No: | 910634-41-2 | 分子式: | C23H37N5O4S2 | 分子量: | 511.7 |
| CAS No: | 910634-41-2 | ||||
| 分子式: | C23H37N5O4S2 | ||||
| 分子量: | 511.7 | ||||
一种选择性的有丝分裂特异性运动蛋白 Eg5 抑制剂，具有抗肿瘤的活性。
Litronesib, also known as LY2523355, is a n inhibitor of the kinesin-related motor protein Eg5 with potential antineoplastic activity. Litronesib selectively inhibits the activity of Eg5, which may result in mitotic disruption, apoptosis and consequently cell death in tumor cells that are actively dividing. The ATP-dependent Eg5 kinesin-related motor protein (also known as KIF11 or kinesin spindle protein-5) is a plus-end directed kinesin motor protein that plays an essential role during mitosis, particularly in the regulation of spindle dynamics, including assembly and maintenance. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
