中文名称: Indisulam
英文名称: Indisulam
CAS No: 165668-41-7
分子式: C14H12ClN3O4S2
分子量: 385.85
I10365 Indisulam ≥98% (psaitong)
包装规格:
5mg 10mg 25mg 50mg in glass bottle
溶解性:
溶于DMSO(20mg/ml 超声)
产品描述:

一种碳酸酐酶抑制剂,具有抗癌活性。Indisulam(E7070)是细胞周期G1期的靶向化合物。Indisulam(E7070)通过抑制CDK2和周期蛋白E的激活,引起G1/S转化被阻滞。Indisulam(E7070)通过募集DCAF15诱导RBM39降解来靶向剪接。
Indisulam, also known as E7070, is a carbonic anhydrase inhbitor, is also a novel synthetic sulfonamide that targets the G1 phase of the cell cycle.. The potential antitumor activity of Indisulam was discovered through optimization of the structure-activity relationships of a series of sulfonamide structures. Indisulam causes a blockade in the G1/S transition through inhibition of the activation of both cyclin-dependent kinase 2 and cyclin E. Preclinical studies with Indisulam showed activity in multiple tumor types, most prominently in colon and lung cancer.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

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    *
    *选择对应的单位 *空出希望得到的变量,填写另外两个变量

用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )

  • * = *

连续稀释计算器方程

  • 连续稀释

  • 初始浓度:
  • 稀释倍数:
  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):