中文名称: | 鸦胆亭 | ||||
---|---|---|---|---|---|
英文名称: | Bruceantin | ||||
别名: | 鸦胆停;鸦胆丁 (-)-Bruceantin; NCI165563; NSC165563 | ||||
CAS No: | 41451-75-6 | 分子式: | C28H36O11 | 分子量: | 548.585 |
CAS No: | 41451-75-6 | ||||
分子式: | C28H36O11 | ||||
分子量: | 548.585 | ||||
EINEC: | 165563 | ||||
EINEC: | 165563 |
包装规格:
10mg in glass bottle
溶解性:
溶于DMSO(100mg/mL超声)
产品描述:
从痢鸦胆子中提取,对B16黑色素瘤,结肠癌38,L1210和白血病P388有抑制性。
Bruceantin is a quassinoid originally isolated from B. antidysenterica that has diverse biological activities. It inhibits protein synthesis in HeLa cells, reticulocytes, and reticulocyte lysates (IC50s = 30, 40, and 1,600 nM, respectively). Bruceantin is active against chloroquine-sensitive and -resistant strains of P. falciparum (IC50s = 8 and 13 nM, respectively). It induces apoptosis in HL-60 leukemia and RPMI-8226 multiple myeloma cells (IC50s = 12.2 and 12.8 nM, respectively). Bruceantin (5 mg/kg) induces tumor regression in an RPMI-8226 mouse xenograft model.
Bruceantin is a quassinoid originally isolated from B. antidysenterica that has diverse biological activities. It inhibits protein synthesis in HeLa cells, reticulocytes, and reticulocyte lysates (IC50s = 30, 40, and 1,600 nM, respectively). Bruceantin is active against chloroquine-sensitive and -resistant strains of P. falciparum (IC50s = 8 and 13 nM, respectively). It induces apoptosis in HL-60 leukemia and RPMI-8226 multiple myeloma cells (IC50s = 12.2 and 12.8 nM, respectively). Bruceantin (5 mg/kg) induces tumor regression in an RPMI-8226 mouse xenograft model.
保存条件:
-20℃
UN码:
HazardClass:
危害声明:
安全说明:
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参考文献 & 客户发表文献
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )