| 中文名称: | 阿伐斯汀 促销 | ||||
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| 英文名称: | Acrivastine | ||||
| 别名: | 阿伐斯汀;阿伐司丁 BW825C | ||||
| CAS No: | 87848-99-5 | 分子式: | C22H24N2O2 | 分子量: | 348.44 |
| CAS No: | 87848-99-5 | ||||
| 分子式: | C22H24N2O2 | ||||
| 分子量: | 348.44 | ||||
基本信息
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产品编号： |
A11606 |
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产品名称： |
Acrivastine |
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CAS: |
87848-99-5 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式： |
溶于液体 |
-80℃ |
6个月 |
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分子量： |
348.44 |
-20℃ |
1个月 |
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化学名： |
2-Propenoic acid,3-[6-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-2-pyridinyl]-,(2E)- |
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Solubility (25°C)： |
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体外:
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DMSO |
10mg/mL (28.69mM) |
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Ethanol |
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Water |
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体内(现配现用): |
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＜1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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制备储备液
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浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
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1mM |
2.8699mL |
14.3497mL |
28.6993mL |
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5mM |
0.5740mL |
2.8699mL |
5.7399mL |
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10mM |
0.2870mL |
1.4350mL |
2.8699mL |
生物活性
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产品描述 |
一种用于研究过敏性鼻炎的短效histamine 1受体拮抗剂。 |
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靶点 |
Histamine Receptor |
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体内研究 |
Acrivastine (usually 8mg three times daily) is an effective and well tolerated antihistamine in the treatment of chronic urticaria and allergic rhinitis.Acrivastine is more effective than placebo and similar in efficacy to clemastine or terfenadine in the treatment of seasonal allergic rhinitis.In the treatment of dermatoses in which histamine has a pathogenetic role,the efficacy of acrivastine is superior to that of placebo and similar to that of usual dosages of clemastine,hydroxyzine,chlorpheniramine,cyproheptadine or terfenadine.Acrivastine causes less drowsiness than clemastine,the incidence of adverse effects being indistinguishable from that with placebo or terfenadine.Both 4mg and 8mg acrivastine alleviate the symptoms of seasonal allergic rhinitis with significant improvements in the symptom scores for sneezing,running nose and the calculated overall score.In addition,8mg acrivastine reduces the symptom scores for watery eyes and itchy throat.Acrivastine is both well tolerated and effective in the treatment of seasonal allergic rhinitis. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
